Many web apps that we use are launched from a parent web page using a technology called a popup page. Unfortunately some Ad's are delivered in this same way. However, there are generally only one or two of these depending on the site you are visiting and most web developers no longer rely on this method of pushing Ad's because web browsers block them through the use of the popup blockers by default. It is safe to turn off this technology because the use of the popup blocker usually masks additional issues your computer may have such as malware. If you turn off the popup blocker and you are inundated with Ad's then you have malware that needs to be removed.
To turn off the popup blocker on the Chrome browser do the following:
While in Chrome click on the Settings icon in the upper right corner (three dashed lines) and select "Settings" in the menu. At the bottom of the page click the link for "Show Advanced Settings". In the Privacy section Click the "Content Settings..." button. Scroll down to Popups and select "Allow all sites to show popups". You can also be more selective and just allow certain websites to popup a page by clicking the Manage Exceptions button and in the Hostname Pattern field enter the website address pattern such as infinitecampus.org.